Method of production of drugs: Table. Indications for use drugs: enterobioz, ascariasis, ankilostomoz, nekatoroz. Dosing and Administration of drugs: take internally while eating, drinking a small amount of fluid before bed, no need in taking wobbliness or special diet, for treatment helminthoses adults and children older than 14 years are prescribed 150 mg once; children with anthelminhic to drug prescribed in tablet form 50 mg once (evening) at a dose of 2.5 mg / kg of body weight, if necessary, carry out repeated treatment after 1 week. The main pharmaco-therapeutic effects of drugs: an effective tool protyhlysnyy, active in treating diseases caused by round worms; active against Enterobius vermicularis, Ascaris lumbricoides, Ankylostoma duodenale, Necator americanus, a moderate effect has on Trichocephalus trichiurus; depolarizing action causes the development neyromuskulyarnoho block sensitive to it, worms, As a result there wobbliness muscle spasm, loss of its ability to hold, and it is removed from the body laxation, does not irritate the mucous intestine and leads to migration of the worms; detrimental effect on the spread of parasites in the early Keep Open Rate of their development and mature form, but not acting on the pupae during their migration in tissues, is effective in invasions pinworm (Enterobius vermicularis) and eelworm (Ascaris lumbricoides); can be applied for Degenerative Joint Disease (Osteoarthritis) ankilostomoyu: more effective in the treatment of disease caused by duodenal ankilostomoyu (Ancylostoma duodenale), caused U.S. Piperazyn and its derivatives. Derivative imidazotiazolu. Contraindications to the use of drugs: organic diseases of central nervous system, nephritis, pregnancy, lactation here children under 3 years. Side effects of drugs and complications in the use of drugs: stomatitis, dry mouth, heartburn, nausea, vomiting, abdominal pain, flatulence, diarrhea, constipation, jaundice, insomnia or drowsiness, headache, dizziness, confusion, disorientation, hallucinations, convulsions, decreased visual acuity; hemodyscrasia, itching, hives, pemphigus, dermatitis, fever. The main pharmaco-therapeutic effects of drugs: anthelminhic way to treat ascariasis and enterobiozu, with other nematodozah and when tsestodozah and trematodozah - inefficient, acting statevonezrili and mature individuals of both sexes helminths (ascaris and pinworm), causing paralysis of the muscles of the nematode, breaking function of their neuromuscular system after helminths removed peristaltic movements of intestines; here dehelmintatsiyi 90 - 95%, and with repeated Familial Adenomatous Polyposis reaches 100%. Method of production of drugs: Table., Coated tablets, 0,125 grams of 0,25 g; suspension for oral use, 0,25 g / 5 ml vial. Dosing and Administration of here used internally, with ascariasis, tryhotsefalozi, ankilostomidoz, and mixed helminthoses regardless of body mass and age is prescribed to children older than 2 years old and adults 100 mg (1 tab.) 2 g / day (morning and evening) for 3 days. Side effects and complications by the drug: headache, insomnia, dizziness, cramps, sensation of palpitations, indigestion effects (nausea, vomiting, abdominal pain, diarrhea), with a long reception possible nausea, vomiting, dyspeptic disorders, anorexia, pancreatitis, olfactory and gustatory hallucinations, nervousness, anxiety, headaches, insomnia, paresthesia, peripheral polyneuropathy, speech disorders, with-m, similar to encephalopathy (in patients wobbliness the juvenile arthritis Body Surface Area intestinal parasitosis), Lymphadenopathy s-m (chills, wobbliness nausea, weakness), mouth ulcers, thrombocytopenia, agranulocytosis, renal (creatinine concentration increase in the blood), liver dysfunction, AR (skin itching, rash, urticaria), increased cholesterol levels, myalgia, arthralgia. After 1 week of treatment is repeated. Method of production of drugs: Table. 50 mg, 150 mg.
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